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Sequencing Unlimited


Rosemary will demonstrate the scalability of Oxford Nanopore sequencing during her talk, both across the devices and also different approaches — from targeted sequencing to whole-genome sequencing and high-throughput applications. Using nanopore technology, it’s possible to sequence anything from short fragments such as amplicons or cell free DNA to ultra-long fragments. With long, native reads, nanopore sequencing can access challenging regions of the genome, resolve complex structural variants, call methylation, and phase over 98% of the genome — all from the same dataset. Rosemary will cover all of these aspects of the technology before introducing the latest Oxford Nanopore developments and upgrades. These include Q20+ chemistry, the latest R10.4 pore, and duplex reads — which are in field now delivering raw read accuracies greater than 99%.

Authors: Rosemary Sinclair Dokos

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