Coast-to-coast spread of SARS-CoV-2 during the early epidemic in the United States

9 SARS-CoV-2 genomes were generated with MinION sequencing, within 24 h of receiving the RNA samples; their ‘quick turnaround period was really testament to the technology’.

Phylogenetic data showed the 1st detected SARS-CoV-2 cases in Connecticut were likely from domestic introduction, not international travel.

Joseph: because of this risk from domestic importation, unified control efforts are needed across the U.S. to monitor and prevent spread of the outbreak in the U.S.

Cost-effective MinION sequencing: 121 SARS-CoV-2 genomes on just 4 MinION Flow Cells, by flow cell nuclease-flushing and re-use.

Authors: Joseph Fauver