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Clone-and haplotype-specific copy number variation inference in heterogeneous bulk tumour samples


Characterise haplotype-specific large-scale copy number variations (CNVs) and novel hypo/hypermethylation in heterogeneous tumours via whole-genome nanopore sequencing.

Download the poster to discover:

  • How cancer progression is associated with the accumulation of somatic mutations and clonal expansion
  • A CNV analysis workflow using whole-genome nanopore sequencing, including allele phasing
  • How long, direct nanopore sequencing reads facilitate haplotype-specific CNV and methylation analysis in tumour samples

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