Advantages of long reads for genome assembly

Overview

The ability to sequence and assemble whole genomes or specific genomic regions of interest is delivering new insights into a variety of applications, such as human health and disease, metagenomics, evolutionary biology, and crop breeding. However, legacy technologies use short-reads sequencing, which limits accurate genome assembly and generates fragmented reference genomes with gaps in complex genomic regions.

This white paper explores how nanopore sequencing overcomes these challenges with any-length nanopore reads to generate high-quality complete genomes with fewer contigs.

In this white paper, you will:

• Learn the importance of genome assembly and its recent developments
• Discover the limitations of legacy sequencing technologies
• Find out how nanopore sequencing overcomes these limitations
• Read real-world case studies of how researchers are utilising nanopore sequencing to deliver new insights