SRY: an effective method for sorting long reads of sex-limited chromosome

Most of available reference genomes are lack of the sequence map of sex-limited chromosomes, that make the assemblies uncompleted. Recent advances on long reads sequencing and population sequencing raise the opportunity to assemble sex-limited chromosomes without the traditional complicated experimental efforts.

We introduce a computational method that shows high efficiency on sorting and assembling long reads sequenced from sex-limited chromosomes. It will lead to the complete reference genomes and facilitate downstream research of sex-limited chromosomes.