ROBIN - revolutionising brain tumour classification with real-time Oxford Nanopore sequencing and adaptive sampling


Webinar Overview

In this webinar, Prof. Matt Loose showcases ROBIN, (Rapid nanopOre Brain IntraoperatIve classificatioN), a tool that uses Oxford Nanopore technology for rapid and comprehensive molecular profiling of central nervous system (CNS) tumours.

ROBIN’s integration of real-time analysis, dynamic adaptive sampling, and cutting-edge algorithms represents a transformative advancement in brain tumour classification, potentially reducing turnaround times from weeks to hours.

Key learnings:

- Real-time nanopore sequencing results enable rapid (intraoperative) methylation classification of tumours.

- ROBIN incorporates several molecular profiling bioinformatics pipelines to streamline CNS tumour classification and molecular profiling in under 24 hours.

Authors: Dr Ellie Juarez (Market Segment Manager for Oncology, Oxford Nanopore Technologies), Prof. Matt Loose (Professor of Computational and Developmental Biology, University of Nottingham)