London Calling 2023: Building a comprehensive knowledge graph of novel proteins with long-read metagenomic sequencing and global partnerships

Basecamp Research is built on the belief that nature has already designed solutions to our planet's greatest challenges. We have developed partnerships with over 50 public, private, and governmental biodiversity guardians in 65 expeditions across 18 countries to map unexplored microbial biodiversity. In doing so, we build bioliteracy and molecular biology capacity, and create a sustainable and ethical route to the biotechnology industry for biodiversity assets.

Our protein knowledge graph and bespoke analysis suite open the route to the biotechnology industry. We use long-read and polishing platforms for metagenome sequencing, which yield assemblies with longer contigs and more high-confidence annotations than available in public databases. Along with the detailed and standardized environmental and sample metadata, this facilitates cutting-edge protein characterization approaches. We leverage our uniquely contextualized data and novel analytical suite to find biological solutions to previously intractable problems across a range of biotechnology industries.