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Multiomics whole-genome characterisation of a cancer genome using Oxford Nanopore sequencing


LC2025 Tumour-normal PO_1244

Comprehensive identification of somatic and single nucleotide variants (SNVs), structural variants (SVs), and copy number variants (CNVs), as well as epigenetic modifications (5mC and 5hmC) and chromatin accessibility from a single dataset.

Download the poster to find out about:

  • Our end-to-end tumour-normal and tumour-only Oxford Nanopore sequencing workflow
  • Accurate identification, phasing and annotation of somatic SNVs
  • Purity estimation and joint haplotype-resolved somatic SV and CNV calling
  • Multiomics analysis of PTEN in COLO829 including full-length transcriptome sequencing

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