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Emergence of new multi-resistant *Brachyspira hyodysenteriae *in Belgian pigs, revealed by high-quality whole-genome sequencing


Swine dysentery (SD) caused by Brachyspira hyodysenteriae (B. hyodysenteriae) results in substantial economic losses in swine-producing countries worldwide. Outbreaks of SD caused concern in Belgium, given the sudden rise of cases that were admitted to the laboratory Animal Health Care Flanders in 2018-2020. Furthermore, it was feared that treatment with antimicrobial compounds would be hampered due to an increased resistance against commonly used antibiotics. Therefore, an in-depth genomic analysis of antimicrobial resistance and genetic relatedness of Belgian strains was done in this study.

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