Differential CpG methylation analysis with pycoMeth
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As well as determining the nucleotide sequence, with Nanopore sequencing, you able also able to identify RNA or DNA modifications with no additional preparation. There are now a number of methods for the detection of CpG methylation, but downstream analysis is not straightforward, in particular differentially methylated areas of the genome in different experimental conditions. This is why we developed pycometh, together with nanosnake, the workflow streamlines the entire analysis at scale and finalises the project in a user friendly HTML report.
