Accelerating precision oncology research with nanopore sequencing

Whether you missed the event at the conference, or want to see the presentations again, this is a great opportunity to see Oxford Nanopore's lunchtime satellite session from AACR 2024.

Native, PCR-free nanopore sequencing, with unrestricted read lengths, offers a unique view into cancer biology. This allows the identification of single nucleotide variants, structural variants, and epigenetic modifications on a haplotype level — from a single dataset. In this symposium, we explored how these technical benefits open up a new window of understanding into cancer genomes, and featured projects ranging from cancer whole-genome sequencing to cell-free DNA with methylation, and single-cell sequencing.

Authors: Mikhail Kolmogorov, Principal Investigator, National Cancer Institute, National Institutes of Health. Ayse Keskus, Postdoctoral Fellow, National Cancer Institute, National Institutes of Health. • Julie Geyer, Postdoctoral Research Associate, University of North Carolina at Chapel Hill School of Medicine.