Main menu

Span tandem repeats in a single read

Tandem repeats (TRs) are continuously repeated bases and are a type of structural variant (SV). TR expansions are important genetic aberrations that are associated with over 50 neurodegenerative disorders. The study of such diseases requires accurate size determination of the expanded repeat, which has proven to be challenging with legacy sequencing methods such as short-read sequencing. Oxford Nanopore sequencing generates reads of unrestricted length that can span repeat expansions end to end in single reads without the need for PCR, enabling unambiguous size determination.

Resolving repetitive regions with Oxford Nanopore sequencing

入門

MinION Starter Packを購入 ナノポア製品の販売 シークエンスサービスプロバイダー グローバルディストリビューター

お問い合わせ

Intellectual property Cookie policy Corporate reporting Privacy policy Terms & conditions Accessibility

Oxford Nanoporeについて

Contact us 経営陣 メディアリソース & お問い合わせ先 投資家向け Oxford Nanopore社で働く BSI 27001 accreditationBSI 90001 accreditationBSI mark of trust
Japanese flag