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How do I preserve long fragments in my samples?
How do I preserve long fragments in my samples?
To minimise shearing samples (and preserve long-lengths of input/libraries) we recommend:
- mixing your sample and reagents very gently.
- avoid vortexing your long-length DNA samples.
- use of wide-bore pipette tips will also assist in mitigating DNA shearing during your sample and library preparation.
- follow the sample storage recommendations in our protocols for optimal results.
