Translocation and extrachromosomal DNA (ecDNA) detection in cancer using low-pass Pore-C sequencing
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Chromatin conformation capture detects the presence of translocations and ecDNA at low sequencing depth and without the need for breakpoint-spanning reads.
Download the poster to discover:
- More about translocations and extrachromosomal DNA in cancer
- How native Pore-C libraries from cancer cells or tissue can be prepared and analysed
- The unique signatures in Pore-C contact matrices produced by translocations and ecDNA
- About how detected chromosomal anomalies can be validated with nanopore adaptive sampling
