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RNA N6-adenine methylation dynamics impact Hyaloperonospora arabidopsidis resistance in Arabidopsis


Studying N6-adenine methylation (m6A) changes during the biotic stress response in Arabidopsis is challenging with immunoprecipitation techniques. To overcome these challenges, the authors used direct RNA nanopore sequencing to resolve exact m6A positions at single nucleotide resolution. The team discovered m6A changes during the defence response against the parasite, H. arabidopsidis, and concluded that m6A could be a promising target to investigate for improved crop resistance against pathogens.

Authors: Leonardo Furci, Jérémy Berthelier, Hidetoshi Saze

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