Profiling age and body fluid DNA methylation markers
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- Published on: April 4 2024
DNA methylation plays a key role in physiological processes including regulating gene expression and is a widely used biomarker for age prediction and the identification of body fluids. Traditionally, methylation detection relies on independent targeting of CpG sites as part of a multiplexed assay, which requires a complex, multistep workflow.
During this webinar, our expert speaker presented a new approach – using nanopore adaptive sampling for comprehensive methylation profiling.
They illustrated how nanopore adaptive sampling successfully corroborated known CpG markers for age and body fluids and identified potential new age-related methylation sites, outlining its potential in forensics and the clinic.
Watch this webinar to:
- Gain insights into how nanopore adaptive sampling is used to simultaneously detect age and body fluid-specific DNA methylation markers
- Learn how the shift from experimental to computational strategies provides a more comprehensive methylation analysis
- Hear how nanopore adaptive sampling addresses the challenges of methylation detection.
