Main menu

ONT-cappable-seq: a new approach to explore the transcriptional architecture of bacterial viruses


Bacterial viruses (phages) recognize their microbial host, infect it and convert the cell into a virus-producing machine within a matter of minutes.

Classical RNA-sequencing has become the method of choice to study the transcriptional landscape of phage-infected bacteria. However, short-read RNA sequencing approaches generally fail to capture key transcriptional features in dense viral genomes, such as operon structures and transcription start and termination sites.

The elucidation of these elements is fundamental to achieve a global understanding of gene regulation mechanisms during the infection process, to ultimately help develop alternative strategies to combat bacterial pathogens and for the development of SynBio applications inspired by phages.

Download the PDF

入门指南

购买 MinION 启动包 Nanopore 商城 测序服务提供商 全球代理商

纳米孔技术

订阅 Nanopore 更新 资源库及发表刊物 什么是 Nanopore 社区

关于 Oxford Nanopore

新闻 公司历程 可持续发展 领导团队 媒体资源和联系方式 投资者 合作者 在 Oxford Nanopore 工作 职位空缺 商业信息 BSI 27001 accreditationBSI 90001 accreditationBSI mark of trust
Chinese flag