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NCM 2022: Advances in duplex basecalling


In Oxford Nanopore devices, duplex sequencing — in which both DNA strands from a single molecule are sequenced back-to-back — provides substantial accuracy benefits over single-strand sequencing. This talk will introduce duplex sequencing, give an overview of joint basecalling methods, and demonstrate the speed and accuracy of a new approach called Stereo Duplex.

Authors: Katherine Lawrence

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