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Modified bases and synthetic training update


Abstract

Oxford Nanopore’s modified base detection tools have been evolving fast with the release of Remora and the proof of concept that models could be trained from synthetic oligomers. This talk will review our recent progress in the accurate detection of DNA modifications:

  • Upgraded 5mC CpG model for Kit 14
  • New synthetic randomer models
  • Progress on synthetic datasets
Authors: Adrien Leger

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