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Individual cells matter — single-cell data analysis with EPI2ME


Abstract Why limit your single-cell data to only the 5' or 3' end? With Oxford Nanopore, you can sequence full-length transcripts from your 10x cDNA libraries, revealing isoform-specific expression patterns. Learn how our EPI2ME platform enables analysis of these rich datasets in just a few clicks with a cross-platform, end-toend single-cell workflow. Biography Dr. Matt Parker is Director, Clinical Bioinformatics Software at Oxford Nanopore Technologies and sits in the Customer Workflows (EPI2ME) team. The Customer Workflows team produce bioinformatics analysis workflows and platforms (EPI2ME) for the analysis of Oxford Nanopore sequencing data. As a health care and professionals council registered clinical bioinformatician, Matt is interested in the potential of Oxford Nanopore sequencing to improve human health through better genomic diagnostics. Matt and his team are focused on developing medical device grade analysis workflows across infectious diseases, rare disease, and cancer that can be deployed on Oxford Nanopore devices and in the cloud to take Oxford Nanopore sequencing reads and derive meaningful clinical interpretations. Bryan Leland is a Bioinformatics Manager in the Commercial Applications group at Oxford Nanopore Technologies where he works with research hospitals, core facilities, and other external collaborators. Previously, he worked in the Applications team at Inscripta, a CRISPR start-up in Boulder, Colorado. His earlier academic work focused on mechanisms of DNA repair at the NIH and Yale.

Authors: Matt Parker & Bryan Leland

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