AACR 2022: The most comprehensive view of the cancer genome

Direct, PCR-free nanopore sequencing offers a unique view into the human genome, allowing single nucleotide variations, structural variations, phasing, epigenetic modifications and more to be examined in a single sequencing dataset. In this session, we explored how these technical benefits can open up a new window of understanding into the cancer genome, featuring projects ranging from new methods of interrogating hereditary cancer predisposition to rapid insights into paediatric leukaemias. Listen now to hear some of the latest from scientists using nanopore sequencing to access new genomic and transcriptomic information, giving an unprecedented view of the mechanisms involved in cancer progression and evolution.