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Megan L. Noonan

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Job title
Institution
Washington University School of Medicine in St. Louis, USA
Biography

Megan Noonan is a post-doctoral researcher at Washington University School of Medicine in St. Louis, Division of Nephrology. She completed her PhD in Medical and Molecular Genetics at Indiana University, Indianapolis. Her research aims to uncover novel mechanisms of kidney disease progression via dysregulated alternative splicing. She uses nanopore sequencing to better resolve isoforms for more accurate alternative splicing analysis in bulk and single-cell RNA sequencing datasets.

Recent publications

Noonan, M.L. et al. Injury-induced FoxM1 expression in mouse kidney drives epithelial proliferation by a cyclin F dependent mechanism. JCI Insight (2024).
DOI: 10.1172/jci.insight.175416

Noonan, M.L. et al. Osteocyte Egln1/Phd2 links oxygen sensing and biomineralization via FGF23. Bone Research (2023).
DOI: 10.1038/s41413-022-00241-w

Noonan, M.L., Wu, H., and Humphreys, B.D. Long-read sequencing identifies loss of proximal tubule spliceosome gene Srsf7 as a driver of inflammation through alternative splicing. Journal of the American Society of Nephrology 34(11S):842 (2023).
DOI: 10.1681/ASN.20233411S1842a

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