Epigenetics and Epigenomics in Health and Disease 2022

These are exciting times for discovering the biological scope and the mechanisms of action for DNA and RNA molecules, which have great impact in health and diseases, including cancer and neurodevelopmental disorders. Epigenetic mechanisms, such as postranslational modifications of chromatin (DNA and histones), play pivotal roles in development, cell differentiation and cell identity. Inappropriate regulation of epigenetic mechanisms has been implicated in common human diseases. Moreover, there has been a recent explosion of activity in the fields of RNA epigenetics and non-coding RNAs, which have become integral parts of the field of gene expression.

This International Meeting on “Epigenetics and Epigenomics in Health and Disease” will integrate different sessions on: transcription and chromatin in gene regulation, DNA modifications, RNA epigenetics, non-coding RNA, epigenomic tools. Besides bringing the newest findings on epigenetic mechanisms, a special focus will be dedicated to discuss novel and promising therapeutic drugs aimed at reversing specific epigenetic alterations.

The meeting will gather scientists using diverse approaches, such as molecular biology, cell biology genetics, epigenomics, and biochemistry. Researchers from pharmaceutical companies and clinicians working in different fields but sharing the same interests will also find the meeting an ideal opportunity to meet, discuss and summarize their work.

Hear from Philipp Rescheneder, Director, Genomic Applications Bioinformatics, Oxford Nanopore Technologies presenting 'Epigenomics at haplotype resolution: simultaneously resolve variants and methylation in a single data set with Oxford Nanopore Sequencing' on Day 1, at 14:00. See the full programme here.