Software downloads
EPI2ME Desktop Application
EPI2ME provides best practice bioinformatics analyses for nanopore sequencing:
- Simply and easily analyse your sequencing data
- Transparent: all our analyses are open source
- Cloud upload optional
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Getting Started
Quick start guideVersion: 5.3.0
Release date: 11/5/2025
Approved use: For research use only
This release of EPI2ME Desktop introduces the new 2ME architecture, an update that simplifies workflow distribution and enhances accessibility for all EPI2ME users. The 2ME distribution mechanism consolidates workflow dependencies into a single file, streamlining deployment and enabling offline installation.
Alongside this update, the EPI2ME CDN is launching to provide a standardised and controlled channel for workflow delivery, simplifying IT networking requirements.
These improvements reinforce EPI2ME’s mission to empower users in all environments to make sense of their sequencing.
Nanopore Community
The Nanopore Community contains many useful resources, including:
Protocols
Build or select a protocol using our range of tools.
Bioinformatics
Build or select a protocol using our range of tools.
Extraction methods
Detailed extraction protocols and specific recommendations are provided for various tissue types.
