NCM 2022: Determination of the centromere protein A landscape at single-molecule resolution

The spacing and density of CENP-A are still unknown, yet very crucial to understand part of the mechanism of chromosome segregation. - We aim to use Directed-Methylation with Long-read sequencing (DiMeLo-Seq) to study the epigenetic properties of centromeres, including centromere protein density and positioning.

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