Resource Centre
58 results
William Jeck: Nanopore sequencing and rapid fusion testing – a ‘killer app’ in molecular pathology
- Nanopore Community Meeting
- Oncology
- Structural variation
December 14 2018
Whole-genome sequencing with long reads reveals complex structure and origin of structural variation in human genetic variations and somatic mutations in cancer
- Long-read
- Whole genome
- Human genomics
- Cancer research
- Oncology
- SNVs
- Structural variation
- Variant calling
- MinION
April 29 2021
Whole genome assembly of human papillomavirus by nanopore long-read sequencing
- Oncology
- Cancer research
- Clinical research
- Microbiology
- Infectious disease
- MinION
- DNA
- Long-read
January 4 2022
In vivo genetic screen identifies a SLC5A3-dependent myo-inositol auxotrophy in acute myeloid leukemia
- Cancer research
- Oncology
- Long-read
- DNA
- GridION
- Clinical research
- Targeted
- Methylation
- Epigenetics
December 22 2020
Transcriptome profiling for precision cancer medicine using shallow nanopore cDNA sequencing
- RNA
- Transcriptome
- Gene expression
- Cancer research
- Oncology
- Long-read
- Bioinformatics
- MinION
February 9 2023
Transcriptional silencing of ALDH2 in acute myeloid leukemia confers a dependency on Fanconi anemia proteins
- Human genomics
- Cancer research
- Clinical research
- Oncology
- DNA
- Targeted
- Epigenetics
- Direct analysis
- GridION
October 23 2020
TP53 gene mutation analysis in chronic lymphocytic leukemia by nanopore MinION sequencing
- MinION
- Clinical research
- Cancer research
- Oncology
- Targeted
- Amplicons
- DNA
- Variant calling
October 10 2016
TEQUILA-seq: a versatile and low-cost method for targeted long-read RNA sequencing
- Splice variation
- MinION
- GridION
- Transcriptome
- Oncology
- Sequence capture
- RNA
- cDNA
August 8 2023
A survey of rare epigenetic variation in 23,116 human genomes identifies disease-relevant epivariations and novel CGG expansions
- Methylation
- Epigenetics
- Structural variation
- Long-read
- Clinical research
- Cancer research
- Oncology
- Targeted
- Amplicons
- DNA
March 26 2020
Suberoyl bis-hydroxamic acid reactivates Kaposi’s sarcoma-associated herpesvirus through histone acetylation and induces apoptosis in lymphoma cells
- Oncology
- Clinical research
- MinION
- Transcriptome
- Gene expression
- Virus
- cDNA
- RNA
September 10 2020
Single-molecule RNA sequencing reveals IFNγ-induced differential expression of immune escape genes in merkel cell polyomavirus–positive MCC cell lines
- MinION
- RNA
- cDNA
- Gene expression
- Oncology
- Cancer research
- Microbiology
- Clinical research
November 22 2021
Single-cell multi-omics reveals elevated plasticity and stem-cell-like blasts relevant to the poor prognosis of KMT2A-rearranged leukemia
- Clinical research
- Cancer research
- Oncology
- Single cell
- Gene fusions
- RNA
- cDNA
- Targeted
- GridION
December 7 2020
Simultaneous methylation and chromatin accessibility profiling on breast cancer models
- London Calling
- Cancer research
- Oncology
- DNA
- Long-read
- Epigenetics
May 24 2018
Simultaneous detection and comprehensive analysis of HPV and microbiome status of a cervical liquid-based cytology sample using Nanopore MinION sequencing
- Microbiology
- Virus
- Microbiome
- Metagenomics
- Targeted
- Amplicons
- 16S
- Clinical research
- MinION
- Long-read
- DNA
- gDNA
- Cancer research
- Oncology
December 18 2019
Short and long-read genome sequencing methodologies for somatic variant detection; genomic analysis of a patient with diffuse large B-cell lymphoma
- Clinical research
- Human genomics
- Oncology
- Cancer research
- Long-read
- Structural variation
- Variant calling
- SNVs
- gDNA
- DNA
- Whole genome
- PromethION
March 19 2021
Robust methylation-based classification of brain tumors using nanopore sequencing
- Methylation
- Human genomics
- Oncology
- Cancer research
- gDNA
- DNA
- MinION
- Long-read
March 8 2021
Real-time detection of BRAF V600E mutation from archival hairy cell leukemia FFPE tissue by nanopore sequencing
- Clinical research
- Cancer research
- Oncology
- Targeted
- FFPE
- DNA
- Amplicons
- MinION
- Variant calling
- SNVs
December 13 2017
Rapid identification of genomic structural variations with nanopore sequencing enables blood-based cancer monitoring
- Human genomics
- Clinical research
- Cancer research
- Oncology
- DNA
- gDNA
- Targeted
- Structural variation
- Whole genome
- Amplicons
- MinION
- GridION
- PromethION
- Real-time
- Long-read
November 15 2019
Rapid-CNS2: Rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof of concept study
- Oncology
- Cancer research
- Real-time
- MinION
- Variant calling
- Clinical research
- Human genomics
March 22 2022
The potential impact of nanopore sequencing on human genetics.
- MinION
- Human genomics
- Whole genome
- Exome
- Cancer research
- Oncology
- Sequence capture
- Amplicons
July 26 2017