Predicition of rRNA Modifications in Single Molecule Resolution with hidden Markov Models
- Published on: June 19 2020
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Hypothesis: Different combinations of rRNA modifications may alter ibosome behaviour in translation.
Aim: Classification of individual ribosomes based on their specific modification patterns and their possible impacts on translation.
Approach: Building a prediction model to distinguish modified nucleotides from the rest.
Results: Prediction of a single modification site with 77% accuracy.
