NCM 2022: The San Francisco estuary microbiome: circularizing genomes of uncultured bacteria, Archaea, Phage, and Phage Satellites
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To fully understand a microbial system requires knowledge of the genomes of the organisms comprising the system. In the past, this has meant devising a plethora of schemes for sequencing and assembling metagenomes derived from environmental samples followed by attempts to bin the resulting contigs into something that resembles a genome. Generating complete circular genomes was rare due to the short reads typically being used.