Genomic phasing using read-level, haplotype-specific methylation calls with native DNA sequencing
- Published on: May 15 2023
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Incorporating haplotype-specific methylation calls generates larger phase blocks than those achieved using traditional approaches that rely solely on heterozygous single-nucleotide variants
Download the poster to discover:
- How to use genomic and epigenomic variants to phase diploid whole-genome datasets
- How genomic variant based phase blocks can be extended and connected with methylation calls
- How incorporating methylation calls can lead to improved contiguity and unchanged error rates
- How medically relevant genes are more likely to be phased together using MethPhaser
