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Contaminating manufacturing plasmids and disrupted vector genomes present in liver tissue following adeno-associated virus gene therapy

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Authors: Sarah Buddle, Li-An K Brown, Sofia Morfopoulou, Oscar Enrique Torres Montaguth, Mariacristina Scoto, Vanessa Herder, Anil Dhawan, Julianne R Brown, Laura Atkinson, Angelika Kopec, Dee Davis, Nathaniel Storey, Luis Campos, Neil Sebire, Hannah Macpherson, Jasmaine Lee, Richard Orton, Giovanni Baranello, Patawee Asamaphan, Georgios Ilia, Rajvinder Karda, Holly Belfield, ISARIC 4C Investigators, Malcolm Gracie Semple, J Kenneth Baillie, John Counsell, Simon Waddington, Emma C Thomson, Francesco Muntoni, Judith Breuer
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  • Published on: January 14 2025
  • Source: medRxiv

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