Main menu

An atlas of expressed transcripts in the prenatal and postnatal human cortex


Identifying novel disease transcripts is challenging when using short-read data, as there is limited ability to obtain full-length isoforms. Here the authors use nanopore sequencing to generate an atlas of full-length transcripts from prenatal and postnatal cortexes, identifying de novo mutations in genes that are linked to neurological conditions. This resource allows researchers to explore the molecular underpinnings of brain development and disease.

Authors: Rosemary A. Bamford, Szi Kay Leung, V. Kartik Chundru, Aaron R. Jeffries, Jonathan P. Davies, Alice Franklin, Xinmu Chen, Andrew McQuillin, Nicholas Bass, APEX consortium, Emma Walker, Paul O’Neill, Ehsan Pishva, Emma L. Dempster, Eilis Hannon, Caroline F. Wright, Jonathan Mill

Getting started

Buy a MinION starter pack Nanopore store Sequencing service providers Channel partners

Quick links

Intellectual property Cookie policy Corporate reporting Privacy policy Terms & conditions Accessibility

About Oxford Nanopore

Contact us News Media resources & contacts Investor centre Careers BSI 27001 accreditationBSI 90001 accreditationBSI mark of trust
Spanish flag