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Oxford Nanopore Technologies cancer research media tool kit

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Introduction to our work in cancer research

The genetic underpinnings of cancer are diverse and many types of genomic aberration — from SNVs to SVs, fusion transcripts, and epigenetic modifications (e.g. DNA/RNA methylation) — can fuel or signal disease. As a result, researchers have traditionally relied on multiple techniques to identify and analyse different forms of cancer.

Nanopore sequencing is disrupting that model by delivering a streamlined and rapid solution for complete characterisation of cancer samples with the potential to be deployed in handheld devices near to the sample. The technology combines many new features in DNA analysis, sequencing any length of DNA fragment, including ultra-long reads in excess of 4 Mb, spanning complex structural variants, including DNA/RNA methylation, and achieving real-time results.


Resources

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White paper: Accelerating cancer research through comprehensive genomic analysis

Read here
Cancer cells 2

Workflow: Characterising structural variants in FFPE cancer research samples

Read here
More resources

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