Overview
Over the course of 5 days in Denver, Colorado, the American Society of Human Genomics 2024 Annual Meeting will cover a broad spectrum of topics including new technologies, applications, and research to showcase the most compelling genetics and genomics science of the year. Exhibits will be open from November 6th to 8th.
Oxford Nanopore will be located at booth 203, and will host an Industry Education Session, two CoLabs, on-booth activities, and an off-site evening event. Register to confirm your spot at our events!
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Industry Education Session
Oxford Nanopore will host an Industry Education during the ASHG conference.
Location: Rooms 109-113
Date: Thursday, November 7th
Time: 12:00 pm — 1:00 pm MT
Session details and agenda to be posted soon.
CoLabs
Oxford Nanopore will be hosting two CoLabs at the ASHG 2024 annual meeting. CoLabs are 30-minute sessions hosted in the exhibit hall to showcase offerings from our industry experts and thought leaders. View session details below and register to attend.
Unlock the potential of pharmacogenomics with Oxford Nanopore sequencing
Location: CoLab Theater 2
Date: Wednesday, November 6th
Time: 2:30 pm — 3:00 pm MT
Pharmacogenomics (PGx) is vital for personalized medicine, enabling tailored drug prescriptions and dosages. This improves drug efficacy, reduces adverse reactions, and enhances patient safety. In this talk, Scott Hickey, Director of Genomics Applications, will discuss PGx's role in modern healthcare, including the impact of genetic variations on drug metabolism and the significance of personalized treatment plans.
Traditional methods struggle to resolve complex genetic regions like CYP2D6, which is crucial for metabolizing 20-25% of prescribed drugs. We'll demonstrate how Nanopore sequencing can accurately genotype PGx panels and assemble CYP2D6 by sequencing 96 patient-derived cell lines with known variants. Our approach uses scalable methods like the TWIST Alliance Long-Read PGx Panel, adaptive sampling, Cas9 enrichment, and long-range PCR, achieving high target capture efficiency (~60%) and read lengths over 5 kb. Our bioinformatic tool, Chinook, excels in reconstructing the CYP2D6 locus and ensures 100% concordance in PGx gene analysis with the EPI2ME pipeline.
Telomere-to-telomere genome assembly using nanopore long and ultra-long reads
Location: CoLab Theater 1
Date: Thursday, November 7th
Time: 4:00 pm — 4:30 pm MT
In this CoLab presentation, Sean McKenzie, Associate Director of Genomics Applications Bioinformatics, will demonstrate how to use Nanopore sequencing as a cost-effective method for genome assembly. By combining improved Nanopore ultra-long read accuracy with the innovative HERRO algorithm for pre-assembly read correction, we will show how you can construct a telomere-to-telomere (T2T) assembly backbone with just two flowcells of Nanopore ultra-long reads using the Verkko assembler.
With Nanopore Pore-C data for long-range phasing, our approach surpasses previous multi-technology methods. Most human chromosomes can be assembled T2T without manual intervention, significantly reducing costs and lab work. This streamlined method makes T2T genome assemblies more accessible and feasible for widespread adoption, paving the way for advanced genomic research.
Evening reception
Join Oxford Nanopore at our evening reception!
Time: 7:30 pm ~ 11:00 pm MT
Date: Thursday, November 7th
Venue: 1134 Broadway
Location: 1134 N Broadway, Denver, CO 80203
Please register to join members of Oxford Nanopore Technologies and users of nanopore technology for an evening of substantial canapés, drinks, and networking. The Oxford Nanopore Technologies team and speakers from our conference events will be on hand all evening at 1134 Broadway, just a five minute drive from the conference venue!
To register, please submit the form on this page.
Registration is required due to limited space. Your place will be confirmed by an email from events@nanoporetech.com. Please note, you will need an ASHG badge to attend the reception. Attendees must be age 21+.
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