Benchmarking small nucleotide and structural variant discovery and 5mC quantification in human samples

Long and accurate nanopore reads with inbuilt methylation information are ideal for characterising all sizes of sequence variants as well as interrogating epigenetic modifications across the genome.

Download the poster to discover:

  • How nanopore sequencing accuracy and read lengths enable calling of small nucleotide and structural variants with high sensitivity and specificity, even in difficult genomic regions  of the human genome
  • The benchmarking of nanopore methylation analysis, which reveals lower bias, higher mapping rates, greater reproducibility, and faster analysis than what is seen with bisulfite data

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