a member of the Nanopore support team aiding a customer at a conference

Contact support

You can contact our Customer Services and Technical Services teams round the clock using the contact support function.

Contact support

What does it mean if pores are becoming saturated?

During a sequencing run, you might observe an increase in inactive channels on your duty time plot. If the mux scan shows an increase in saturated pores then this indicates additional membrane stress.

Membrane stress can be caused by changes in salt concentration or pH and the presence of surfactants.

The mux scan plot below shows an example of a run with increasing saturated pores.

Contaminants can cause osmotic imbalance and membrane stress. The effects of certain contaminants are described on the Contaminants Know-how page.

Please consider an alternative extraction method that does not result in contaminant carryover, and always make sure you QC your input DNA/RNA according to our guidelines.

Getting started

Your first experiment

Find out more

The Nanopore Community

Find out more

Managing your devices and account

Find out more

Nanopore technology explained

Find out more

Community posts

Full community members have access to posts and private channels