Dr Matthew Loose, Head of Next Generation Sequencing Service, Nottingham University talks to the MinION commnity.
Large capital investments are needed for second-generation sequencing equipment, which has led to the concentration of human genome sequencing efforts in specialized sequencing centers.
Detection of genomic inversions remains challenging. Many existing methods primarily target inversions with a non repetitive breakpoint, leaving inverted repeat (IR) mediated non-allelic homologous recombination (NAHR) inversions largely unexplored.
Dr Matthew Loose