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Telo-seq: native sequencing of individual telomeres on R10 nanopores using a bespoke 3’ adapter


Date: 15th May 2023

Telo-seq uses ligation of specific adapters to chromosome ends, and base-calling models trained on telomeric repeat sequences to enable precise telomere mapping and telomere length characterisation

Download the poster to discover:

  • How telo-seq uses telomere-specific adapters to target the ends of chromosomes
  • How a customised R10 base-caller identifies and maps enriched telomere sequences
  • The value of telomere variant information uncovered by phasing telomeric reads 
  • How mapping haplotyped reads provides high resolution measurement of telomere-length

Download the PDF

Register your interest for Telo-seq here.

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