RNA sequencing: The value of full-length transcripts without bias
28th March 2018
RNA sequencing (referred to as RNA-Seq with traditional sequencing technologies) has led to unprecedented advances in all fields of biology and medicine. It has been an invaluable tool for the study of human genetics and the pathology associated with disease. Transcript isoform expression and usage, for example, is a prominent source of variation between healthy and diseased tissues in a number of medical conditions, including cancer. RNA sequencing is also instrumental in identifying fusion transcripts present in a growing number of disorders.
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