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Native telomere sequencing of individual chromosomes using 3’ end adapter ligation


Date: 5th December 2022

Direct Oxford Nanopore adapter ligation to chromosome ends and base-calling models trained on telomeric repeat sequences enables precise telomere length and methylation analysis in human cells.

Download the poster to discover:

  • The process of Oxford Nanopore adapter ligation to the telomere ends with the use of short telomere adapters
  • More about a customised base-caller that identifies and maps enriched telomere sequences
  • More about mapping individual telomere reads which enables comparative telomere length measurements
  • How methylation patterns in native telomeres can be analysed using Remora

Download the PDF

Register your interest for Telo-seq here.

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