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The NanoTYPETM HLA assay: rapid, comprehensive, high-resolution HLA typing using nanopore sequencing

Poster

Date: 5th December 2022

Use long nanopore reads to accurately identify SNPs, phase haplotypes, and perform high-resolution genotyping within the most polymorphic region of the human genome — the Human Leukocyte Antigen (HLA) region.

Download the poster to discover:

  • The importance of the HLA locus in the context of tissue transplantation
  • A workflow combining long-range PCR with rapid library preparation, nanopore sequencing, and data analysis, for targeted analysis of the HLA region
  • How the workflow has the potential to generate rapid results, important for deceased donor typing
  • How higher levels of multiplexing could be used, demonstrating the potential of this assay for routine registry typing

Download the PDF

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