A multi-omics approach to characterise epithelial to mesenchymal transition in lung cancer metastasis
PosterDate: 15th May 2023
Evaluate cells undergoing the phenotypic transition from epithelial to mesenchymal states using full-length transcriptomics, targeted methylation, and chromatin conformational changes with Pore-C.
Download the poster to discover:
- The morphological changes underlying epithelial-mesenchymal transition (EMT) in cancer cells
- How to perform a multi-omic analysis of the EMT process in cancer, from the generation of whole-genome, transcriptome, and Pore-C nanopore sequence data
- How to use differential transcript expression analysis and Pore-C chromatin conformation capture data to understand genomic changes involved in tumour metastasis
- How to use adaptive sampling to explore methylation differences at EMT loci