Products

Discover nanopore sequencing

What can it do? How does it work? Our platform performance and accuracy

Explore products

Prepare Sequence Analyse
Applications
Store Resources Support About
Support

Comprehensive analysis of hereditary cancers with PCR-free targeted sequencing using adaptive sampling

Poster

Date: 15th May 2023

Simple targeted sequencing of the human genome on a MinION Flow Cell allows SNP calling and phasing, methylation analysis, and genome-wide, low-pass copy number variant (CNV) analysis from a single nanopore sequencing dataset.

Download the poster to discover:

  • How adaptive sampling can be used for targeted analysis of a gene panel, here encompassing 201 cancer-related genes and >15,000 promoter regions across the human genome
  • How SNP calling and variant phasing can be performed on targeted nanopore sequence data, facilitating the study of compound heterozygosity
  • How targeted sequencing with adaptive sampling is completely PCR-free, enabling you to directly capture methylation patterns
  • How rejected, 'off-target' reads from adaptive sampling can be used to analysis CNVs 

Download the PDF

Recommended for you