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cDNA sequencing Research Spotlight

Literature

Date: 22nd July 2019

Nanopore long reads enable full-length cDNA sequencing, allowing both quantitative and qualitative analysis of gene expression, and detailed characterisation of novel transcripts.

Anthony Bayega and his team investigated gene expression in the olive fly embryo at different developmental stages using nanopore long reads. These data enabled an in-depth characterisation of transcriptional mechanisms involved in olive fly embryo development. Insights into the gene expression signatures of sex determination can be used to identify potential targets for sex-specific genetic control of this agricultural pest.

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