In nanopore sequencing devices, electrolytic current signals are sensitive to base modifications, such as 5-methylcytosine (5-mC). Here we quantified the strength of this effect for the Oxford Nanopore Technologies MinION sequencer.
npInv: accurate detection and genotyping of inversions mediated by non-allelic homologous recombination using long read sub-alignment
Characterization of structural variations and chromothripsis in nanopore sequencing data of human genomes
Benchmarking of de novo assembly algorithms for Nanopore data reveals optimal performance of OLC approaches.