Wed 22nd February 2017
Fungal infections are a serious threat to human health and responsible for the death of one million people annually, particularly deadly to those with a weakened immune system. Added to which, resistance to anti-fungal medication is on the rise. Following a fungal outbreak in an intensive care unit, Jo Rhodes was approached by clinicians to investigate and identify the outbreak and source.
In her talk Jo will share how the long reads from nanopore sequencing enabled the creation of a “gold standard” reference genome and helped:
- the rapid response in species identification
- to place the outbreak into a global context and find the origin
Q&A with Jo will follow her talk
Jo Rhodes is a bioinformatician and molecular epidemiologist at Imperial College London. Currently, she is an early career research fellow attached to the Fisher and Armstrong-James groups, with links to clinical scientists at the Royal Brompton Hospital. She explores the use of genomics to diagnose and survey fungal infectious diseases. Recently, she has demonstrated the importance of mixed genotype infections of Cryptococcus in HIV patients in sub-Saharan Africa. She has also generated a reference genome on the MinION platform for a hospital outbreak of the emerging fungal pathogen Candida auris.
Dr Johanna Rhodes
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