Mon 10th July - Thu 13th July 2017
Recent research has shown that RNA decay makes major contributions to biological regulation and cellular surveillance in eukaryotes. Fundamental RNA turnover pathways now being studied at the atomic level are conserved among yeasts, animals and plants, while each system also exhibits diversification. Central themes include regulation of mRNA turnover by AU-rich elements, and the effects of microRNAs on RNA decay and translation. In addition, numerous mechanisms eliminate RNAs that fail quality control checkpoints. This EMBO conference will also be a major forum for discussion of the latest findings relating to altered RNA turnover in disease, and the identification of potential therapeutic targets.
Keble College, Oxford, United Kingdom
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