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Genome research with nanopore sequencing technology
Complete understanding of genetic variation. Sequence whole genomes, targeted regions or full-length RNA transcripts. Fully characterise structural variation (SV), repetitive regions, single nucleotide variation (SNV) haplotype phasing, RNA splice variants, isoforms, fusion transcripts and epigenetic modifications.
- Ultra-long reads resolve challenging regions Accurate characterisation of structural variants and repetitive regions delivers improved genome assemblies and more comprehensive targeted resequencing analysis.
- Analyse full-length RNA transcripts Direct, real-time sequencing of complete RNA strands. Or sequence full-length cDNA, either with or without PCR amplification.
- Explore epigenetic modifications by direct sequencing Direct and simultaneous detection of DNA or RNA modifications with sequencing data.
- Streamlined workflow and real-time analysis Library prep in just 10 minutes with immediate analysis of real-time data; delivers rapid access to results.
- Simple and scalable Fully scalable nanopore sequencing, without any change to the library preparation method. Experiments can be scaled using the MinION™, GridION™ or PromethION™.
How are your peers using nanopore technology?
Which approach is best for you?
DNA Sequencing
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RNA Sequencing
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Prepare
- Streamlined library prep in as little as 10 minutes
- From just 400 ng DNA
- PCR option for very low input amounts
- Multiplexing options for more cost-effective analysis
Sequence
- Real-time sequencing on MinION, GridION or PromethION
Analyse
- Real-time analysis with on device or local infrastructure basecalling.
- Detect DNA modifications using open source tools
Prepare
- Streamlined library prep in as little as 2 hours
- From as low as 50 ng polyA-tailed RNA
- Multiplexing options for more cost-effective analysis
Sequence
- Real-time sequencing on MinION, GridION or PromethION
Analyse
- Real-time analysis of up to 10 million full-length reads (PCR cDNA kit)
- On device or local infrastructure basecalling
- Detect RNA modifications using open source tools (direct RNA kit).